|
|
|
| Welcome |
Common Myths The Cause of Weight Problems Food Body Weight Nutritional Facts Glycaemic Index Fats aren't Fats Food Combination Metabolic Hormones Weight Loss Tools Calories in Foods Inspirational Quotes Weight Loss Methods Weight Loss Drugs Diets Weight Loss Surgery Supplements Weight Control Athletes Arthritis Lifestyle Exercise Time Management Recipes Recipe Collection |
Human Growth HormoneDirect effects are the result of growth hormone binding its receptor on target cells. Fat cells (adipocytes), for example, have growth hormone receptors, and growth hormone stimulates them to break down triglyceride and supresses their ability to take up and accumulate circulating lipids.Indirect effects are mediated primarily by a insulin-like growth factor-1 (IGF-1), a hormone that is secreted by the liver and other tissues in response to growth hormone. It mediates HGH's growth promoting effects. IGF-1 stimulates the proliferation of cartiladge cells and HGH appears to contribute to their differentiation into mature cells. IGF-1 also stimulates proliferation and differentiation of muscle cells as well as their uptake of amino acids and protein synthesis. Protein metabolism: In general, growth hormone stimulates protein anabolism by increasing protein synthesis (see above) and inhibiting protein oxidation. Fat metabolism: Growth hormone enhances the utilization of fat by stimulating triglyceride breakdown and oxidation in fat cells. Carbohydrate metabolism: supresses the abilities of insulin to stimulate uptake of glucose in peripheral tissues and enhance glucose synthesis in the liver. Somewhat paradoxically, administration of growth hormone stimulates insulin secretion, leading to hyperinsulinemia. The production of Growth Hormone is regulated by many factors including sleep, stress, nutrition, exercise. The hypothalamus produces the peptide hormone Somatostatin, which inhibits HGH release, and HGH release hormone, which stimulates synthesis and secretion as response to low blood sugar levels. The hormone Grehlin, which is produced in the stomach, also stimulates HGH production by binding to receptors on producing cells. What is Human Growth Hormone?Also called Somatotropin.Glycoprotein made of 190 amino acids, produced in the anterior pituitary gland. |
 |
Copyright 2004 Dr Angie Hayes |  |