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AdrenalinAlso called Epinephrin: stress hormone, which is stored in electron dense granulas together with ATP and several neuropeptides. Its release is triggered by Acetylcholine as a reaction to the many forms of stress, for example exercise, hypoglycaemia, trauma.Its effects are all related to life saving efforts: Increased rate and force of contraction of the heart muscle Constriction of blood vessels resulting in increased blood pressure Dilation of bronchioles to facilitate breathing Stimulation of lipolysis in fat cells: to preserve blood glucose and provide energy Increased metabolic rate: oxygen consumption and heat production Medullary hormones also promote breakdown of glycogen in skeletal muscle to provide glucose for energy production. Dilation of the pupils for improved vision in the dark Inhibition of certain "non-essential" processes: an example is inhibition of gastrointestinal secretion and motor activity. The effects are mediated via 4 different types of receptors: alpha 1, alpha 2, beta 1 and beta 2 which use different cellular signals. What is Adrenalin?Produced in the adrenal medulla from the amino acid Tyrosine.Intermediates are Dihydroxy Phenylalanine (DOPA), Dopamine, Noradrenalin and Adrenalin. |
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Copyright 2004 Dr Angie Hayes |  |